Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt

CAS NO.：1021868-77-8
Empirical Formula: C18H11N4Na4O14PS2
Molecular Weight: 694.36
MDL number: MFCD03093192
Update Date: 2026-09-12 18:51:19

What is Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt?

The Uses of Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt

PPNDS is a potent and selective antagonist of the P2X1 receptor.

Biological Activity

Potent and selective P2X 1 receptor antagonist (pK B = 7.43 in rat vas deferens). Up to 52-fold selective over P2Y 1 receptors, and selective over ecto-nucleotidase, α 1A -adrenoceptors, A 1 , A 2B , H 1 and M 3 receptors.

Storage

Desiccate at -20°C

Properties of Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt

storage temp.	−20°C
solubility	H₂O: 38 mg/mL
form	solid
color	dark red
Water Solubility	Soluble to 100 mM in water

Safety information for Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt

Computed Descriptors for Pyridoxal-5'-phosphate-6-(2'-naphthylazo-6'-nitro-4',8'-disulfonate) tetrasodium salt

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