PYRIDINE-2-SULFONYL FLUORIDE
Synonym(s):2-Pyridinesulfonyl Fluoride
- CAS NO.：878376-35-3
- Empirical Formula: C5H4FNO2S
- Molecular Weight: 161.15
- MDL number: MFCD09265513
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-06-04 16:00:12
What is PYRIDINE-2-SULFONYL FLUORIDE?
The Uses of PYRIDINE-2-SULFONYL FLUORIDE
Novel thermally stable deoxyfluorination reagent with a broad substrate scope of alcohols.
The Uses of PYRIDINE-2-SULFONYL FLUORIDE
2-pyridinesulfonyl fluoride can be used for the deoxyfluorination of primary and secondary alcohols in combination with an amidine or guanidine base. In comparison with other common deoxyfluorination reagents, for example, DAST exhibits less elimination side products in direct comparison on certain substrates.
Properties of PYRIDINE-2-SULFONYL FLUORIDE
| Melting point: | 29-34°C |
| Boiling point: | 234.9±13.0 °C(Predicted) |
| Density | 1.421±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | solid |
| pka | -3.93±0.19(Predicted) |
| color | White to Almost white |
Safety information for PYRIDINE-2-SULFONYL FLUORIDE
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PYRIDINE-2-SULFONYL FLUORIDE
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