PTZ-343
- CAS NO.：101199-38-6
- Empirical Formula: C15H16NNaO3S2
- Molecular Weight: 345.41
- MDL number: MFCD08275674
- EINECS: 1592732-453-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-15 14:23:52
What is PTZ-343?
Description
PTZ-343 is a phenothiazine (PTZ) derivative with chemical name sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. The free acid of PTZ-343 has molecule weight 343. For the convenience of commucation, we call it as PTZ-343. PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). It acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission.
The Uses of PTZ-343
Sodium 3-?(10H-?Phenothiazin-?10-?yl)?propane-?1-?sulfonate can be used in biological and analytical studies of a portable chemiluminescence imaging immunoassay for simultaneous detection of different isoforms of prostate specific antigen in serum.
in vitro
PTZ-343 behaves as electron transfer mediator, it reacts with HRP-II to release HRP and a enhance (PTZ-343) radical. The enhancer (PTZ-343) radical quickly oxidizes luminol anions to induce light emission.
Properties of PTZ-343
| Melting point: | >232°C (dec.) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly, Heated) |
| form | Solid |
| color | Off-White to Pale Yellow |
| Stability: | Hygroscopic |
| InChI | InChI=1S/C15H15NO3S2.Na.H/c17-21(18,19)11-5-10-16-12-6-1-3-8-14(12)20-15-9-4-2-7-13(15)16;;/h1-4,6-9H,5,10-11H2,(H,17,18,19);; |
Safety information for PTZ-343
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PTZ-343
| InChIKey | LAXVHQHEZUKIAE-UHFFFAOYSA-N |
| SMILES | C(N1C2=CC=CC=C2SC2C=CC=CC1=2)CCS(O)(=O)=O.[NaH] |
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