PROTRIPTYLINE HYDROCHLORIDE
Synonym(s):N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride
- CAS NO.:1225-55-4
- Empirical Formula: C19H22ClN
- Molecular Weight: 299.84
- MDL number: MFCD00072057
- EINECS: 214-956-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 23:13:44
What is PROTRIPTYLINE HYDROCHLORIDE?
The Uses of PROTRIPTYLINE HYDROCHLORIDE
Monoamine reuptake inhibitor; tricyclic antidepressant.
What are the applications of Application
Protriptyline hydrochloride is A norepinephrine uptake blocker
brand name
Vivactil (Odyssey).
General Description
Protriptyline hydrochloride, N-methyl-5H-dibenzo[a,d]-cycloheptene-5-propylamine hydrochloride, 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene hydrochloride(Vivactil), like the other compounds under consideration, isan effective antidepressant. The basis for its chemical namingcan be seen by consulting the naming and the structureof imipramine. Protriptyline is a structural isomer of nortriptyline.Inactivation can be expected to involve the relativelylocalized double bond. Because it is a monomethylcompound, its sedative potential is low.
Biochem/physiol Actions
Norepinephrine uptake blocker.
Properties of PROTRIPTYLINE HYDROCHLORIDE
| Melting point: | 169-171° |
| Flash point: | 9℃ |
| storage temp. | 2-8°C |
| solubility | H2O: soluble50mg/mL |
| form | powder |
| pka | 8.2(at 25℃) |
| color | white to off-white |
| Stability: | Hygroscopic |
Safety information for PROTRIPTYLINE HYDROCHLORIDE
| Signal word | Danger |
| Pictogram(s) |
![]() Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PROTRIPTYLINE HYDROCHLORIDE
New Products
Cyclopropane-1,1-dicarboxylic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity tert-Butyl (2S)-[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamate 4-amino-2-fluoro-N- methylbenzamide 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine N-Boc-1,4-butanediamine 4-Bromo-2-fluoro-N-methylbenzamide valeronitrile 3-chlorobenzyl cyanide 3,4 Dimethoxy Benzylcyanide 3,4 Diethoxy Benzylcyanide 2-Chloro Benzylcyanide 3-Hydroxypropionitrile 5-azidovalericacid 6,6'-bis(difluoromethoxy)-2,2'-bis((3,4-dimethoxypyridin-2-yl)methylsulfinyl)-1H,1'H-5,5'-bibenzo[d]imidazole (1-((2'-(2-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (1-((2'-(1-((1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methyl)-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol (4-Methoxyphenyl) hydrazine HydrochlorideRelated products of tetrahydrofuran




![5H-dibenzo[a,d]cycloheptene](https://img.chemicalbook.in/CAS/GIF/256-81-5.gif)

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