Prostaglandin E1 Impurity 4

CAS NO.：21003-46-3
Empirical Formula: C20H34O5
Molecular Weight: 354.48
MDL number: MFCD00065736
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-11 16:31:51

What is Prostaglandin E1 Impurity 4?

Description

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E₁ (8-iso PGE₁) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF_2α.

The Uses of Prostaglandin E1 Impurity 4

8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors.

The Uses of Prostaglandin E1 Impurity 4

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α.[Cayman Chemical]

Definition

ChEBI: 8-Isoprostaglandin E1 is a prostanoid.

What are the applications of Application

8-iso Prostaglandin E1 is an isoprostane with potency similar to PGF2α

Properties of Prostaglandin E1 Impurity 4

Melting point:	77-79 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling point:	529.3±50.0 °C(Predicted)
Density	1.131±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
form	A light yellow crystalline solid
pka	4.77±0.10(Predicted)