13,14-DIHYDROPROSTAGLANDIN E1

Synonym(s):(9α,11α,13E,15S)-9,11,15-Trihydroxy-6-oxoprosta-13-en-1-oic acid;6-Ketoprostaglandin F_1α;6-Oxo-prostaglandin F_1α

CAS NO.：58962-34-8
Empirical Formula: C20H34O6
Molecular Weight: 370.48
MDL number: MFCD00135222
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-27 23:44:07

13,14-DIHYDROPROSTAGLANDIN E1 Structural

What is 13,14-DIHYDROPROSTAGLANDIN E1?

Description

6-keto prostaglandin F_1α (6-keto PGF_1α) is the inactive, non-enzymatic hydrolysis product of PGI₂. 6-keto PGF_1α serves as a useful marker of PGI₂ biosynthesis in vivo. When [³H]-PGI₂ is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [³H]-6-keto PGF_1α.

The Uses of 13,14-DIHYDROPROSTAGLANDIN E1

6-Ketoprostaglandin F1α is the stable hydrolysis product of prostacyclin (P839060), an eicosanoid which prevents the formation of platelet plugs and an effective vasodilator.

What are the applications of Application

6-Keto-prostaglandin F1α is a PGI 2 hydrolysis product used as a marker for PGI 2

Definition

ChEBI: A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position.

Properties of 13,14-DIHYDROPROSTAGLANDIN E1

Boiling point:	575.3±50.0 °C(Predicted)
Density	1.191±0.06 g/cm3(Predicted)
RTECS	UK8428300
storage temp.	−20°C
solubility	ethanol: 10 mg/mL, clear, faintly yellow
pka	4.69±0.10(Predicted)
form	White to off-white solid.
BRN	2821925

Safety information for 13,14-DIHYDROPROSTAGLANDIN E1

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H317:Sensitisation, Skin
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P321:Specific treatment (see … on this label). P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.