Propiverine hydrochloride
Synonym(s):α,α-Diphenyl-α-propoxyacetic acid hydrochloride 1-methyl-4-piperidyl ester;α-Phenyl-α-propoxybenzeneacetic acid 1-methyl-4-piperidinyl ester hydrochloride;(1-Methylpiperidin-1-ium-4-yl) 2,2-diphenyl-2-propoxyacetate chloride;1-Methyl-4-piperidyl diphenylpropoxyacetate hydrochloride
- CAS NO.：54556-98-8
- Empirical Formula: C23H30ClNO3
- Molecular Weight: 403.94
- MDL number: MFCD01672343
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 09:27:42
What is Propiverine hydrochloride?
Description
Propiverine hydrochloride is a new urological agent developed for pollakuria and aconuresis. It appears to exhibit anticholinergic properties and in animal experiments inhibited KCl induced contractions in the bladder and ileum.
Chemical properties
Off-White Solid
Originator
Apogepha (Germany)
The Uses of Propiverine hydrochloride
Propiverine is used in treatment of urinary incontinence. Propiverine is an anticholinergic.
What are the applications of Application
Propiverine, Hydrochloride is used for treatment of urinary incontinence
Definition
ChEBI: Propiverine hydrochloride is a diarylmethane.
brand name
Mictonorm; Mictonetten
General Description
Propiverine hydrochloride drug is a tertiary amine with spasmolytic and analgesic properties. This drug exerts neurotropic and musculotropic effects on the urinary bladder and smooth muscles. Propiverine hydrochloride has a half-life of 20 hours.
Biochem/physiol Actions
Propiverine is an antimuscarinic drug used for the treatment of overactive blaqdder and urinary incontinence. Propiverine and/or its metabolites also have calcium channel blocking properties in addition to antimuscarinic activity, which may contribute to the clinical activity.
Clinical Use
Treatment of urinary frequency, urgency and
incontinence
Neurogenic bladder instability
Drug interactions
Potentially hazardous interactions with other drugs
Anti-arrhythmics: increased risk of antimuscarinic
side effects with disopyramide.
Metabolism
Propiverine is extensively metabolised by intestinal and
hepatic enzymes. Four metabolites were identified in
urine; two of them are pharmacologically active and may
contribute to the therapeutic efficacy.
Propiverine and its metabolites are excreted in the urine,
bile and faeces.
Properties of Propiverine hydrochloride
| Melting point: | 224-226°C |
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
| CAS DataBase Reference | 54556-98-8(CAS DataBase Reference) |
Safety information for Propiverine hydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. |
Computed Descriptors for Propiverine hydrochloride
Propiverine hydrochloride manufacturer
New Products
Mirtazapine Impurity C/Mirtazapine Lactam Impurity Cyclopropane-1,1-dicarboxylic acid [1]Benzothieno[2,3-c]pyridine, 1,7-dichloro-8-methyl- (S)-3-Fluoro-pyrrolidine hydrochloride Cyclobutylamine 1-Bromo-2-Methoxy-3-Nitrobenzene 3-Oxocyclobutane-1-carboxylicacid (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2-chloro-7-cyclopentyl-N,N-dimethylpyrrolo [2,3-d]pyrimidine-6-carbox amide 4-amino-2-fluoro-N- methylbenzamide N-(2-chloropyrimidin-4-yl)-N,2,3- trimethyl-2H- indazol 6-amine 5-Chloro-3- Methyl -1,3-2-benzoxazol-2(3H)-one 4-Bromo-2-fluoro-N-methylbenzamide N-Boc-1,4-butanediamine 4-Dimethylamino pyridine 2-Chlorotrityl Chloride 4-Bromoaniline 5-Bromo-2-chlorobenzoic acid 1,2,3,9-Tetrahydro-4(H)-carbazol-4-oneRelated products of tetrahydrofuran
You may like
-
54556-98-8 Propiverine hydrochloride 98%View Details
54556-98-8 -
54556-98-8 99%View Details
54556-98-8 -
Propiverine hydrochloride 98%View Details
54556-98-8 -
Propiverine hydrochloride CAS 54556-98-8View Details
54556-98-8 -
KT-474 98+View Details
2432994-31-3 -
2,3-Difluoro-6-methoxybenzyl Chloride 98+View Details
1073435-67-2 -
2-(6-(benzyloxy)-3,4-dihydronaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2477812-43-2 98+View Details
2477812-43-2 -
101894-09-1 4-Hydroxy-6-methyl-1-(4-methylphenyl)-2-naphthalenecarboxylic acid 98+View Details
101894-09-1