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HomeProduct name listPropargyl-PEG4-Sulfone-PEG4-t-butyl ester

Propargyl-PEG4-Sulfone-PEG4-t-butyl ester

  • CAS NO.:2055024-43-4
  • Empirical Formula: C26H48O12S
  • Molecular Weight: 584.72
  • MDL number: MFCD30182061
  • Update Date: 2025-04-18 09:51:07
Propargyl-PEG4-Sulfone-PEG4-t-butyl ester Structural

What is Propargyl-PEG4-Sulfone-PEG4-t-butyl ester?

Description

Propargyl-PEG4-Sulfone-PEG4-t-butyl ester is a PEG linker containing a propargyl group and t-butyl protected carboxyl group acid. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The t-butyl protected carboxyl group (COOH) prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling conditions. The protected acid can be deprotected by acidic or basic hydrolysis. The hydrophilic PEG spacer increases solubility in aqueous media.

Properties of Propargyl-PEG4-Sulfone-PEG4-t-butyl ester

Boiling point: 647.7±55.0 °C(Predicted)
Density  1.131±0.06 g/cm3(Predicted)

Safety information for Propargyl-PEG4-Sulfone-PEG4-t-butyl ester

Computed Descriptors for Propargyl-PEG4-Sulfone-PEG4-t-butyl ester

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