Carcinine dihydrochloride

CAS NO.：57022-38-5
Molecular Weight: 0
MDL number: MFCD22200567
EINECS: 000-000-0
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 04:17:31

What is Carcinine dihydrochloride?

The Uses of Carcinine dihydrochloride

Carcinine dihydrochloride is a benzylamine derivative produced by the reaction of malic acid with dehydroascorbic acid. It has anti-aging, antioxidant, anti-inflammatory, protective and sunscreen properties. It also protects against premature aging, UV-induced damage and apoptosis. It is commonly used in anti-aging formulations, especially for sensitive skin. In addition, Carcinine dihydrochloride has been used to study its effects on dopaminergic neuronal degeneration.

Biological Activity

Carcinine dihydrochloride (β-alanyl histamine) is a selective histamine H3 antagonist, 100-1000-fold selective for H3 over H2 and H1, that also functions as an antioxidant and as a chemical chaperone to reduce non-enzymatic glycation of proteins and maintain native folding of proteins. Carcinine can scavenge a toxic product, called 4-hydroxynonenal (4-HNE), obtained during lipid oxidation. It has a protective role from oxidative damage on photoreceptor cells. Carcinine also exhibits lipid-peroxidase activity.

Properties of Carcinine dihydrochloride

storage temp.	Inert atmosphere,Room Temperature
solubility	H2O: >15mg/mL
form	powder
color	white to beige
InChI	InChI=1S/C8H14N4O.2ClH/c1-2-11-8(13)6(3-9)7-4-10-5-12-7;;/h4-6H,2-3,9H2,1H3,(H,10,12)(H,11,13);2*1H

Safety information for Carcinine dihydrochloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.

Computed Descriptors for Carcinine dihydrochloride

InChIKey	WGTMERJVZVYSBG-UHFFFAOYSA-N
SMILES	C(NCC)(=O)C(C1=CNC=N1)CN.[H]Cl.[H]Cl

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