PONCIRIN

Synonym(s):(S)-5,7-Dihydroxy-4′-methoxyflavanone-7-[2-O-(α-L-rhamnopyranosyl)-β-D-glucopyranoside];4′-O-Methylnaringin;Isosakuranetin-7-neohesperidoside

CAS NO.：14941-08-3
Empirical Formula: C28H34O14
Molecular Weight: 594.57
MDL number: MFCD23380546
EINECS: 239-020-1
SAFETY DATA SHEET (SDS)
Update Date: 2025-12-05 14:33:18

What is PONCIRIN?

Chemical properties

Off-white powder

The Uses of PONCIRIN

Poncirin is a natural bitter flavanone glycoside present in many species of citrus fruits which has various biological benefits such as antioxidant, antimicrobial, anti-inflammatory and anti-cancer activities. Main constituent used in traditional Chinese medicine for inflammation, asthma, and infection diseases.

Definition

ChEBI: (2S)-poncirin is a flavanone glycoside that is 4'-methoxy-5,7-dihydroxyflavanone attached to a neohesperidose (alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranose) residue via a glycosidic linkage. It has been isolated from the fruits of Poncirus trifoliata and exhibits inhibitory activity against liopolysaccharide (LPS)-induced prostaglandin E2 and interleukin-6 (IL-6) production. It has a role as a plant metabolite. It is a monomethoxyflavanone, a flavanone glycoside, a disaccharide derivative, a neohesperidoside and a member of 4'-methoxyflavanones. It is functionally related to a 4'-methoxy-5,7-dihydroxyflavanone.

Properties of PONCIRIN

Melting point:	210°C
Boiling point:	900.1±65.0 °C(Predicted)
Density	1.59
storage temp.	Store at -20°C
solubility	Soluble in methan
form	neat
pka	7.15±0.40(Predicted)
form	Solid
color	Yellow
BRN	74301