pNPS-DHA

CAS NO.：2454246-25-2
Empirical Formula: C28H36N2O5S
Molecular Weight: 512.66
Update Date: 2026-04-21 10:31:43

What is pNPS-DHA?

Biological Activity

pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1 It inhibits degranulation of RBL-2H3 mast cells (IC50 = 15 μM). pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice.

References

1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)

Properties of pNPS-DHA

Density	1.121±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Methyl Acetate: Soluble
pka	4.32±0.10(Predicted)

Safety information for pNPS-DHA

Computed Descriptors for pNPS-DHA

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