pNPS-DHA
- CAS NO.：2454246-25-2
- Empirical Formula: C28H36N2O5S
- Molecular Weight: 512.66
- Update Date: 2026-05-28 05:59:13
What is pNPS-DHA?
Biological Activity
pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1 It inhibits degranulation of RBL-2H3 mast cells (IC50 = 15 μM). pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice.
References
1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)
Properties of pNPS-DHA
| Density | 1.121±0.06 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Methyl Acetate: Soluble |
| pka | 4.32±0.10(Predicted) |
Safety information for pNPS-DHA
Computed Descriptors for pNPS-DHA
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