Piperidine hydrochloride
- CAS NO.：6091-44-7
- Empirical Formula: C5H11N.ClH
- Molecular Weight: 121.61
- MDL number: MFCD00012770
- EINECS: 228-033-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is Piperidine hydrochloride?
Chemical properties
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The Uses of Piperidine hydrochloride
Piperidine hydrochloride is used an intermediate in the manufacture of active pharmaceutical ingredients like anti Parkinsonan agent Biperiden; anti depressant agent Clocapramine hydrochloride and muscle relaxant tolperisone.
The Uses of Piperidine hydrochloride
Reagent for synthesis of:
- Quinoline selenium compounds
- Peripheral seratonin 5-HT3 receptor ligands
Reactant for synthesis of phthalazinone derivatives as topically active phosphodiesterase 4 inhibitors
Reactant for:
- Mannich reactions
- Asymmetric hydrogenation of quinolines
- Chemoselective reductive amination of carbonyl compounds
Purification Methods
Crystallise the salt from EtOH/diethyl ether in the presence of a small amount of HCl. [Beilstein 20 H 6, 20 II 10, 20 III/IV 295, 20/2 V 13.]
Properties of Piperidine hydrochloride
| Melting point: | 245-248 °C(lit.) |
| Boiling point: | 347.05℃ |
| Density | 1,12 g/cm3 |
| vapor density | 2.94 (vs air) |
| vapor pressure | 63.6 mm Hg ( 37.8 °C) |
| Flash point: | >230 °F |
| storage temp. | Store below +30°C. |
| solubility | >1500g/l |
| form | Solid:crystalline |
| PH | 6-8 (111g/l, H2O, 20℃) |
| Water Solubility | soluble |
| Sensitive | Hygroscopic |
| BRN | 3611699 |
| CAS DataBase Reference | 6091-44-7(CAS DataBase Reference) |
| EPA Substance Registry System | Piperidine hydrochloride (6091-44-7) |
Safety information for Piperidine hydrochloride
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H301:Acute toxicity,oral |
| Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for Piperidine hydrochloride
| InChIKey | VEIWYFRREFUNRC-UHFFFAOYSA-N |
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