picromycin
- CAS NO.：19721-56-3
- Empirical Formula: C28H47NO8
- Molecular Weight: 525.68
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-30 08:50:00
What is picromycin?
The Uses of picromycin
Pikromycin is an inhibitor of Prolyl endopeptidase.
What are the applications of Application
Pikromycin is an inhibitor of Prolyl endopeptidase
Definition
ChEBI: A macrolide antibiotic that is biosynthesised by Streptomyces venezuelae.
Enzyme inhibitor
This polyketide (FW = 525.68 g/mol; CAS 19721-56-3; bitter-tasting solid; low water solubility; soluble in benzene and acetone) from Actinomyces spp., and originally spelled pikromycin, was the first identified macrolide antibiotic. Picromycin is most likely produced as the inactive diglucoside and liberated extracellularly as the active antibiotic through the action of a b-glucosidase.
Storage
+4°C
Properties of picromycin
| Melting point: | 169.5℃ |
| alpha | D24 +8.2° (c = 3.5 in ethanol); D20 -33.5° (c = 2.07 in chloroform); D24 -50.2° (c = 6.3 in chloroform) |
| storage temp. | Store at -20°C |
| solubility | DMSO: soluble |
| form | A crystalline solid |
| pka | 11.15±0.70(Predicted) |
| Boiling point: | 688.1±55.0 °C(Predicted) |
| Density | 1.14±0.1 g/cm3(Predicted) |
| color | White crystalline |
Safety information for picromycin
Computed Descriptors for picromycin
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