PICROLONIC ACID

Chemical properties

beige to ochre-yellow powder

The Uses of PICROLONIC ACID

Reagent for the isolation of amines as crystalline π-complexes.Picrolonic acid is an analytical reagent used for the estimation of calcium, magnesium, lead, strontium and thorium. It is also used for the analysis of alkaloids, tryptophan and phenylalanine.

The Uses of PICROLONIC ACID

As reagent for alkaloids, tryptophan, phenylalanine, and for the detection and estimation of calcium.

The Uses of PICROLONIC ACID

With calcium(II), lead(II) and thorium(IV) the reagent gives complexes which are practically insoluble in water. The high molecular weight crystalline complexes can be used to advantage for the accurate determination of minute amounts of various metals.
The reagent has also proved suitable for the spectrophotometric determination of calcium. Calcium picrolonate is transformed by bromine water in alkaline medium to a red, water-soluble complex. The absorption of this compound is constant for about two days and it also follows the Beer-Lambert Law.

What are the applications of Application

Picrolonic acid is used in the analysis of alkaloids, Ca2+ determination, and the isolation of amines

Purification Methods

Crystallise picrolic acid from water or EtOH (solubility is 0.123% at 15o and 1.203% at 100o in H2O; and 1.107% at 0o and 11.68% at 81o in EtOH). It forms Ca, Cu Hg, Mg, Na, Sr, Pb and many other metal complexes [Maquestian et al Bull Soc Chim Belg 82 233 1973, Isaki et al. Chem Ber 74 1420 1941]. [Beilstein 24 H 51, 24 I 218, 24 II 25, 22 III/IV 105.]