Phthalylsulfacetamide
Synonym(s):2-([(4-([Acetylamino]sulfonyl)phenyl)amino]carbonyl)benzoic acid
- CAS NO.：131-69-1
- Empirical Formula: C16H14N2O6S
- Molecular Weight: 362.36
- MDL number: MFCD00020275
- EINECS: 205-035-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:52:03
What is Phthalylsulfacetamide?
The Uses of Phthalylsulfacetamide
antibacterial
Definition
ChEBI: Phthalylsulfacetamide is a member of benzamides.
brand name
Talsigel (Bristol-Myers Squibb); Thalamyd (Schering) [Name previously used: Phthalylsulphacetamide.].
Purification Methods
It is prepared by hydrolysis of N-acetamidosulfophenylpthalimide by boiling for 3hours in 15% aqueous KOH followed by treatment with Norit, filtration and acidification with AcOH. Crystallise the phthalamide from hot H2O or EtOH [Jain et al. J Indian Chem Soc 24 174 1947]. Itis antibacterial.[Beilstein 14 III 2073.]
Properties of Phthalylsulfacetamide
| Melting point: | 196° |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO : ≥ 50 mg/mL (137.98 mM) |
| form | Solid |
| form | neat |
| color | White to off-white |
| EPA Substance Registry System | Benzoic acid, 2-[[[4-[(acetylamino)sulfonyl]phenyl]amino]carbonyl]- (131-69-1) |
Safety information for Phthalylsulfacetamide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Phthalylsulfacetamide
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