PHTHALAMIC ACID
- CAS NO.：88-97-1
- Empirical Formula: C8H7NO3
- Molecular Weight: 165.15
- MDL number: MFCD00025476
- EINECS: 201-871-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:13:13
What is PHTHALAMIC ACID?
The Uses of PHTHALAMIC ACID
Phthalamic Acid is a reactant in the synthesis of phthalimide derivatives with analgesic activity.
The Uses of PHTHALAMIC ACID
Phthalamic acid may be used to synthesize anthranilic acid via reaction with sodium hypochlorite.
Definition
ChEBI: 2-carbamoylbenzoic acid is a carbamoylbenzoic acid.
General Description
Phthalamic acid can be synthesized from the reaction between ammonia and phthalic anhydride by a modified Auger′s method. Kinetic studies of the intramolecular carboxylic-group assisted hydrolysis of amide bond of phthalamic acid provided the value of pseudo-first order rate constant (kobs) as 5.1×10-5sec-1 at pH 1.3-1.8 and 35°C. It undergoes hydrolysis about 105 times faster than benzamide.
Properties of PHTHALAMIC ACID
| Melting point: | 140-143 °C(lit.) |
| Boiling point: | 394.2±25.0 °C(Predicted) |
| Density | 1.368 |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.75±0.10(Predicted) |
| color | White to Off-White |
| BRN | 1868205 |
| CAS DataBase Reference | 88-97-1(CAS DataBase Reference) |
| EPA Substance Registry System | Benzoic acid, 2-(aminocarbonyl)- (88-97-1) |
Safety information for PHTHALAMIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PHTHALAMIC ACID
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline 5-Hydroxy-3,9-dimethyl-7H-benzo[c]fluoren-7-one Methyl 4-(acetyloxy)-6-methoxy-1-(4-methoxyphenyl)-2naphthalenecarboxylate 4-Hydroxy-6,7-dimethoxy-1-phenyl-2naphthalenecarboxylic acid (3,5-Dibromophenyl)[4-(trifluoromethyl)phenyl]methanone (4-butoxyphenyl)(4-fluorophenyl)methanone (4-Bromophenyl)(3,4-dimethoxyphenyl)methanone Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide 4-Ethyl-4-hydroxy-1,4,7,8-tetrahydro-3H,10H-spiro[pyrano[3,4-f]indolizine-6,2'-[1,3]dioxolane]-3,10-dione (E)-N'-(2-cyano-4-nitrophenyl)- N,N-dimethylformimidamide 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid Benzyl-N,4-dimethylpiperidine-3- amine dihydrochloride 5-bromopyridin-2-amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3-chlorobenzyl cyanide 3,4 Dimethoxy BenzylcyanideRelated products of tetrahydrofuran
![2-[(4-chlorophenyl)carbamoyl]benzoic acid](https://img.chemicalbook.in/CAS/GIF/7142-94-1.gif)
![2-([(4-IODOPHENYL)AMINO]CARBONYL)BENZOIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure1/GIF/CB6253884.gif)
![2-([(4-ETHYLPHENYL)AMINO]CARBONYL)BENZOIC ACID](https://img.chemicalbook.in/StructureFile/ChemBookStructure1/GIF/CB8208606.gif)
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