PHOSPHONOACETIC ACID
- CAS NO.：4408-78-0
- Empirical Formula: C2H5O5P
- Molecular Weight: 140.03
- MDL number: MFCD00004311
- EINECS: 224-558-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:12:11
What is PHOSPHONOACETIC ACID?
Chemical properties
White powder
The Uses of PHOSPHONOACETIC ACID
Phosphonoacetic acid inhibits deoxyribo nucleic acid polymerase, especially in viruses. It is used as an antiviral agent. Further, it is used in the preparation of 1-(dimethylamino)-2,2-bis[(dimethylimmonio)-methyl]ethene diperchlorate by reacting with phosphorus oxychloride.
The Uses of PHOSPHONOACETIC ACID
Antiviral.
The Uses of PHOSPHONOACETIC ACID
Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells. It was also used as a phosphorus source for microbial growth in phosphate-independent manner.
Definition
ChEBI: A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
Properties of PHOSPHONOACETIC ACID
| Melting point: | 143-146 °C (lit.) |
| Boiling point: | 490.2±47.0 °C(Predicted) |
| Density | 1.858±0.06 g/cm3(Predicted) |
| refractive index | 1.5180 (estimate) |
| storage temp. | 2-8°C |
| solubility | water: soluble100mg/mL, clear to very slightly hazy, colorless |
| form | Solid |
| pka | 1.74±0.10(Predicted) |
| color | White to off-white |
| Water Solubility | Soluble in water. |
| Sensitive | Hygroscopic |
| BRN | 1764355 |
| CAS DataBase Reference | 4408-78-0(CAS DataBase Reference) |
Safety information for PHOSPHONOACETIC ACID
| Signal word | Warning |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P309:IF exposed or if you feel unwell: P310:Immediately call a POISON CENTER or doctor/physician. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PHOSPHONOACETIC ACID
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