PHOSPHOENOLPYRUVIC ACID TRIS(CYCLOHEXYLAMMONIUM) SALT

Chemical properties

white crystalline powder

The Uses of PHOSPHOENOLPYRUVIC ACID TRIS(CYCLOHEXYLAMMONIUM) SALT

Metabolic intermediate in many kinase reactions

What are the applications of Application

Phosphoenolpyruvic acid, tris(cyclohexylammonium) salt is a metabolic intermediate in many kinase reactions

General Description

Phospho(enol)pyruvic acid is a highly functionalized small molecule. It plays a major role in the metabolism.

Biochem/physiol Actions

Phospho(enol)pyruvic acid is significant in high-phosphate group-transfer function. PEP plays a major role in PEP:sugar phosphotransferase system (PTS) mediated phosphorylation and transport of carbohydrates across the bacterial membrane. It functions to generate natural phosphonates catalyzed by PEP mutase. It plays a key role in the peptidoglycan cell wall biosynthesis.

Purification Methods

Recrystallise it from aqueous Me2CO and dry it in a vacuum. At 4o it is stable for >2 years and has IR at 1721cm-1 (C=O). [Wold & Ballou J Biol Chem 227 301 1957, Clark & Kirby Biochemical Preparations 11 103 1966 for the monocyclohexylamine salt, Beilstein 12 IV 8.]