Dichlorophenylborane

Synonym(s):NSC 93889;Phenylboron dichloride;Phenyldichloroborane

CAS NO.：873-51-8
Empirical Formula: C6H5BCl2
Molecular Weight: 158.82
MDL number: MFCD00013612
SAFETY DATA SHEET (SDS)
Update Date: 2026-05-28 02:51:08

What is Dichlorophenylborane?

Chemical properties

clear colorless liquid

The Uses of Dichlorophenylborane

Dichlorophenylborane is widely used as a catalyst in Antiproliferative macrolide and cell migration inhibitor lactimidomycin and in enantioselective synthesis of polypeptide segments using vinylogous Mukaiyama aldol reactions and in enantioselective Diels-Alder cycloadditions after its reaction with allo-threonine derivatives. It is a stereo selective alkylative ring opening of cyclic anhydrides and in cross-metathesis reaction of amino derivatives with olefines.

The Uses of Dichlorophenylborane

Catalyst for:

Antiproliferative macrolide and cell migration inhibitor lactimidomycin
Enantioselective synthesis of polyketide segments using vinylogous Mukaiyama aldol reactions
Enantioselective Diels-Alder cycloadditions after its reaction with allo-threonine derivatives
Stereoselective alkylative ring opening of cyclic anhydrides
Cross-metathesis reaction of amino derivatives with olefins
Asymmetric acetate aldol reactions
The reaction of aryl aldehydes with styrene and (E)-β-methylstyrene

Properties of Dichlorophenylborane

Melting point:	7 °C
Boiling point:	66 °C11 mm Hg(lit.)
Density	1.224 g/mL at 25 °C(lit.)
refractive index	n20/D 1.545(lit.)
Flash point:	−5 °F
storage temp.	2-8°C
form	Liquid
color	Colorless
Specific Gravity	1.224
Water Solubility	Soluble in water (Reacts violently).
Sensitive	Moisture Sensitive
BRN	2243576
CAS DataBase Reference	873-51-8(CAS DataBase Reference)

Safety information for Dichlorophenylborane

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Corrosion Corrosives GHS05
GHS Hazard Statements	H225:Flammable liquids H314:Skin corrosion/irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.