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HomeProduct name listDichlorophenylborane

Dichlorophenylborane

Synonym(s):NSC 93889;Phenylboron dichloride;Phenyldichloroborane

  • CAS NO.:873-51-8
  • Empirical Formula: C6H5BCl2
  • Molecular Weight: 158.82
  • MDL number: MFCD00013612
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-01-27 09:38:02
Dichlorophenylborane Structural

What is Dichlorophenylborane?

Chemical properties

clear colorless liquid

The Uses of Dichlorophenylborane

Dichlorophenylborane is widely used as a catalyst in Antiproliferative macrolide and cell migration inhibitor lactimidomycin and in enantioselective synthesis of polypeptide segments using vinylogous Mukaiyama aldol reactions and in enantioselective Diels-Alder cycloadditions after its reaction with allo-threonine derivatives. It is a stereo selective alkylative ring opening of cyclic anhydrides and in cross-metathesis reaction of amino derivatives with olefines.

The Uses of Dichlorophenylborane

Catalyst for:

  • Antiproliferative macrolide and cell migration inhibitor lactimidomycin
  • Enantioselective synthesis of polyketide segments using vinylogous Mukaiyama aldol reactions
  • Enantioselective Diels-Alder cycloadditions after its reaction with allo-threonine derivatives
  • Stereoselective alkylative ring opening of cyclic anhydrides
  • Cross-metathesis reaction of amino derivatives with olefins
  • Asymmetric acetate aldol reactions
  • The reaction of aryl aldehydes with styrene and (E)-β-methylstyrene

Properties of Dichlorophenylborane

Melting point: 7 °C
Boiling point: 66 °C11 mm Hg(lit.)
Density  1.224 g/mL at 25 °C(lit.)
refractive index  n20/D 1.545(lit.)
Flash point: −5 °F
storage temp.  2-8°C
form  Liquid
color  Colorless
Specific Gravity 1.224
Water Solubility  Soluble in water (Reacts violently).
Sensitive  Moisture Sensitive
BRN  2243576
CAS DataBase Reference 873-51-8(CAS DataBase Reference)

Safety information for Dichlorophenylborane

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H225:Flammable liquids
H314:Skin corrosion/irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P240:Ground/bond container and receiving equipment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Dichlorophenylborane

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