Dichlorophenylborane
Synonym(s):NSC 93889;Phenylboron dichloride;Phenyldichloroborane
- CAS NO.:873-51-8
- Empirical Formula: C6H5BCl2
- Molecular Weight: 158.82
- MDL number: MFCD00013612
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is Dichlorophenylborane?
Chemical properties
clear colorless liquid
The Uses of Dichlorophenylborane
Dichlorophenylborane is widely used as a catalyst in Antiproliferative macrolide and cell migration inhibitor lactimidomycin and in enantioselective synthesis of polypeptide segments using vinylogous Mukaiyama aldol reactions and in enantioselective Diels-Alder cycloadditions after its reaction with allo-threonine derivatives. It is a stereo selective alkylative ring opening of cyclic anhydrides and in cross-metathesis reaction of amino derivatives with olefines.
The Uses of Dichlorophenylborane
Catalyst for:
- Antiproliferative macrolide and cell migration inhibitor lactimidomycin
- Enantioselective synthesis of polyketide segments using vinylogous Mukaiyama aldol reactions
- Enantioselective Diels-Alder cycloadditions after its reaction with allo-threonine derivatives
- Stereoselective alkylative ring opening of cyclic anhydrides
- Cross-metathesis reaction of amino derivatives with olefins
- Asymmetric acetate aldol reactions
- The reaction of aryl aldehydes with styrene and (E)-β-methylstyrene
Properties of Dichlorophenylborane
| Melting point: | 7 °C |
| Boiling point: | 66 °C11 mm Hg(lit.) |
| Density | 1.224 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | −5 °F |
| storage temp. | 2-8°C |
| form | Liquid |
| color | Colorless |
| Specific Gravity | 1.224 |
| Water Solubility | Soluble in water (Reacts violently). |
| Sensitive | Moisture Sensitive |
| BRN | 2243576 |
| CAS DataBase Reference | 873-51-8(CAS DataBase Reference) |
Safety information for Dichlorophenylborane
| Signal word | Danger |
| Pictogram(s) |
![]() Flame Flammables GHS02 ![]() Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H225:Flammable liquids H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Dichlorophenylborane
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