Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
- CAS NO.：184177-81-9
- Empirical Formula: C23H23N3O3
- Molecular Weight: 389.45
- MDL number: MFCD03784249
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-27 23:09:15
What is Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate?
Description
Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a piperazine derivative that inhibits the growth of gram-positive bacteria.Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)) carbamate is a carbamic acid that binds to the 50S ribosomal subunit of bacteria, preventing transcription and replication. Human activity on human erythrocytes using the membrane clamp technique is frequent. This active form is metabolised by a number of metabolic transformations including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or binding to glucuronic acid.
The Uses of Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
PHENYL {4-[4-(4-HYDROXYPHENYL)PIPERAZIN-1-YL]PHENYL}CARBAMATE is a carboxylic acid ester organic substance and can be used as a pharmaceutical intermediate.
The Uses of Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
[4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic Acid Phenyl Ester is an impurity of Posaconazole (P689600), which is orally active antifungal triazole.
Definition
ChEBI: N-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]carbamic acid phenyl ester is a member of piperazines.
Properties of Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
| Boiling point: | 603.9±55.0 °C(Predicted) |
| Density | 1.296 |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 12.18±0.30(Predicted) |
| InChI | InChI=1S/C23H23N3O3/c27-21-12-10-20(11-13-21)26-16-14-25(15-17-26)19-8-6-18(7-9-19)24-23(28)29-22-4-2-1-3-5-22/h1-13,27H,14-17H2,(H,24,28) |
| CAS DataBase Reference | 184177-81-9 |
Safety information for Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
Computed Descriptors for Phenyl (4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)carbamate
| InChIKey | IKRKMYDCUZYKHX-UHFFFAOYSA-N |
| SMILES | C(OC1=CC=CC=C1)(=O)NC1=CC=C(N2CCN(C3=CC=C(O)C=C3)CC2)C=C1 |
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