Phenol, 4-[3-[4-(1-piperazinyl)phenyl]-1H-indazol-6-yl]-

CAS NO.：2677709-81-6
Empirical Formula: C23H22N4O
Molecular Weight: 370.45
Update Date: 2026-07-27 17:00:41

What is Phenol, 4-[3-[4-(1-piperazinyl)phenyl]-1H-indazol-6-yl]-?

Biological Activity

FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1].

References

[1]. Lewis D Turner, et al. From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J Med Chem. 2022 Jan 27;65(2):1481-1504.

Properties of Phenol, 4-[3-[4-(1-piperazinyl)phenyl]-1H-indazol-6-yl]-

Boiling point:	674.3±55.0 °C(Predicted)
Density	1.266±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO : 62.5 mg/mL (168.71 mM; ultrasonic and warming and heat to 60°C)
pka	9.70±0.15(Predicted)
form	Solid
color	Light yellow to light brown

Safety information for Phenol, 4-[3-[4-(1-piperazinyl)phenyl]-1H-indazol-6-yl]-

Computed Descriptors for Phenol, 4-[3-[4-(1-piperazinyl)phenyl]-1H-indazol-6-yl]-

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