Phenidone
Synonym(s):Phenidone
- CAS NO.：92-43-3
- Empirical Formula: C9H10N2O
- Molecular Weight: 162.19
- MDL number: MFCD00003094
- EINECS: 202-155-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-24 17:36:03
What is Phenidone?
Chemical properties
light beige powder or crystals
The Uses of Phenidone
Phenidone is used as black and white photographic developer.
The Uses of Phenidone
Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.
What are the applications of Application
Phenidone is a dual LO (lipoxygenase) and Cox (cyclooxygenase) inhibitor
Flammability and Explosibility
Not classified
Safety Profile
Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
Properties of Phenidone
| Melting point: | 119-121 °C(lit.) |
| Boiling point: | 288.88°C (rough estimate) |
| Density | 1.1436 (rough estimate) |
| vapor pressure | 0.002Pa at 25℃ |
| refractive index | 1.5600 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: 0.1 g/mL, clear |
| form | White to off-white solid. |
| pka | 9.50±0.30(Predicted) |
| color | White to Light yellow to Light orange |
| Water Solubility | SOLUBLE IN HOT WATER |
| Merck | 14,7309 |
| BRN | 131856 |
| Stability: | Stable, but light sensitive. Incompatible with strong acids, strong oxidizing agents, strong bases. |
| CAS DataBase Reference | 92-43-3(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Phenyl-3-pyrazolidinone(92-43-3) |
| EPA Substance Registry System | 3-Pyrazolidinone, 1-phenyl- (92-43-3) |
Safety information for Phenidone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P391:Collect spillage. Hazardous to the aquatic environment P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for Phenidone
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