Phenethyltrimethoxysilane
Synonym(s):(2-Phenylethyl)trimethoxysilane
- CAS NO.:49539-88-0
- Empirical Formula: C11H18O3Si
- Molecular Weight: 226.34
- MDL number: MFCD00053852
- EINECS: 256-363-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:55:05
What is Phenethyltrimethoxysilane?
The Uses of Phenethyltrimethoxysilane
Trimethoxy(2-phenylethyl)silane is used in the loading and releasing of two anti-cancer drugs, 9-Aminoacridine (9AA) and Camptothecin (CPT) from magnetic mesoporous silica nanoparticle materials.
General Description
Trimethoxy(2-phenylethyl)silane (TMPES) is a phenyl functionalized trialkoxy silane that can be used as a siloxane based precursor.
Properties of Phenethyltrimethoxysilane
| Melting point: | <0°C |
| Boiling point: | 95-96 °C/2 mmHg (lit.) |
| Density | 1.033 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 228 °F |
| form | liquid |
| color | Colorless to Light yellow to Red |
| Specific Gravity | 1.037 |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| BRN | 3031224 |
| EPA Substance Registry System | Silane, trimethoxy(2-phenylethyl)- (49539-88-0) |
Safety information for Phenethyltrimethoxysilane
| Signal word | Warning |
| Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Phenethyltrimethoxysilane
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![Triethoxy[5,5,6,6,7,7,7-heptafluoro-4,4-bis(trifluoromethyl)heptyl]silane](https://img.chemicalbook.in/CAS/20180703/GIF/130676-81-2.gif)







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