PHA-793887
- CAS NO.：718630-59-2
- Empirical Formula: C19H31N5O2
- Molecular Weight: 361.48
- MDL number: MFCD17169992
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-27 17:00:41
What is PHA-793887?
Chemical properties
White to Off-White Solid
The Uses of PHA-793887
PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.
What are the applications of Application
PHA-793887 is a novel pan-Cdk inhibitor inactive against 34 other kinases
Definition
ChEBI: N-[6,6-dimethyl-5-[(1-methyl-4-piperidinyl)-oxomethyl]-1,4-dihydropyrrolo[3,4-c]pyrazol-3-yl]-3-methylbutanamide is a piperidinecarboxamide.
Properties of PHA-793887
| Melting point: | >147°C (dec.) |
| Boiling point: | 596.2±50.0 °C(Predicted) |
| Density | 1.176±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, Refrigerator, under inert atmosphere |
| solubility | DMSO (Slightly), Methanol(Slightly) |
| form | Solid |
| pka | 13.74±0.40(Predicted) |
| color | Off-White to Pale Yellow |
| Stability: | Hygroscopic |
Safety information for PHA-793887
Computed Descriptors for PHA-793887
New Products
9-Mesityl-10-methylacridinium perchlorate Sulfapyridine Fmoc-OSu (R)-(-)-2-Amino-1-propanol Cyclobutanone 5-bromo-4-fluoro-2-nitrobenzaldehyde 4 pentyn 1 ol N-Vinylformamide Phenethyl cinnamate Pyrrolo[1,2-a]pyrimidine-6-carboxylic acid, 4,6,7,8-tetrahydro-4-oxo-, sodium salt (1:1), (6S) Ethyl 3-phenylpropanoate β-Bromostyrene Methacrylate-PEG-Methacrylate, Mn:35000 2,4-Dihydroxyacetophenone 2-Chloro 5-Fluoro Pyridine Vasicinone 2-Chloroisonicotinic Acid Tween 80 or Polysorbate 80 5-Bromo-1-Pentyne 1-(2-Methyl-5-nitrophenyl)guanidine Nitrate Methyl trans-4-Aminocyclohexanecarboxylate Hydrochloride 2-Pentyn-1-oL 4-Nitrobenzotrifluoride N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-methyloxirane-2-carboxamideRelated products of tetrahydrofuran
![(2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol](https://img.chemicalbook.in/CAS/GIF/779353-01-4.gif)
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