PF-6808472
Synonym(s):4-{4-[4-(5-Cyclopropyl-1H-pyrazol-3-ylamino)-6-prop-2-ynylcarbamoyl-pyrimidin-2-yl]-piperazin-1-ylmethyl}-benzenesulfonyl fluoride;XO44
- CAS NO.：2088112-70-1
- Empirical Formula: C25H27FN8O3S
- Molecular Weight: 538.6
- Update Date: 2026-07-27 17:00:41
What is PF-6808472?
Biochem/physiol Actions
PF-6808472 is a cell permeable covalent probe suitable for click chemistry designated to measure kinase selectivity in intact cells. PF-6808472 contains sulfonyl fluoride group, which react with conserved lysine residue within kinase ATP binding site.
Properties of PF-6808472
| Density | 1.452±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| form | powder |
| pka | 11.23±0.46(Predicted) |
| color | white to beige |
Safety information for PF-6808472
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05 |
| GHS Hazard Statements |
H314:Skin corrosion/irritation |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PF-6808472
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