PD 136450
- CAS NO.：139067-52-0
- Empirical Formula: C35H40N4O6
- Molecular Weight: 612.72
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-18 09:52:49
What is PD 136450?
Description
Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. Gastrin (cholecystokinin type B (CCK-B)) receptor antagonists may help to elucidate the physiological role of gastrin, have therapeutic potential as acid antisecretory drugs, and may be of use as adjuvant therapy for gastrin sensitive tumours. The agonist effect of PD-136,450 is mediated via interaction with the gastrin (CCK-B) receptor in the stomach and the CCK-A receptor in the pancreas.
Properties of PD 136450
| Boiling point: | 950.4±65.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| pka | 3.49±0.10(Predicted) |
Safety information for PD 136450
Computed Descriptors for PD 136450
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