PC biotin-PEG3-NHS ester

Synonym(s):PC biotin-NHS ester

CAS NO.：2353409-93-3
Empirical Formula: C36H52N6O15S
Molecular Weight: 840.89
MDL number: MFCD31811520
Update Date: 2026-04-24 14:56:55

What is PC biotin-PEG3-NHS ester?

Description

PC Biotin-PEG3-NHS carbonate ester is a unique amine reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin beads. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

The Uses of PC biotin-PEG3-NHS ester

PC biotin-NHS ester is a unique amine-reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm²).

Properties of PC biotin-PEG3-NHS ester

Melting point:	170 °C
Density	1.39±0.1 g/cm3(Predicted)
storage temp.	-20°C
pka	13.90±0.40(Predicted)

Safety information for PC biotin-PEG3-NHS ester

Computed Descriptors for PC biotin-PEG3-NHS ester

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