PASTEURELLA MULTOCIDA TOXIN
Synonym(s):PMT
- CAS NO.：129876-91-1
- Molecular Weight: 0
- MDL number: MFCD00131803
- Update Date: 2026-01-13 11:23:07
What is PASTEURELLA MULTOCIDA TOXIN?
Biochem/physiol Actions
Pasteurella multocida toxin (PMT) is a bacterial protein toxin produced by few P. multocida serotype A and D strains. It acts as an effective mitogen in numerous cell types in vitro. PMT inhibits osteoblast differentiation by activating the Rho/Rho-associated coiled-coil containing protein kinase (Rho/ROCK) pathway. Infections of PMT cause atrophic rhinitis in pigs and by local dermatonecrosis, respiratory disease in cattle and rabbits. PMT is also a pathogenic agent of dermatonecrosis and bacteremia in humans.
Properties of PASTEURELLA MULTOCIDA TOXIN
| storage temp. | −20°C |
| form | lyophilized powder |
Safety information for PASTEURELLA MULTOCIDA TOXIN
Computed Descriptors for PASTEURELLA MULTOCIDA TOXIN
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