PAQ

CAS NO.：943902-10-1
Empirical Formula: C14H11N3
Molecular Weight: 221.26
Update Date: 2026-04-20 17:00:22

What is PAQ?

Description

PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson’s disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson’s disease induced by MPTP.

Properties of PAQ

Boiling point:	435.4±40.0 °C(Predicted)
Density	1.246±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 2 mg/ml
form	A crystalline solid
pka	1?+-.0.48(Predicted)

Safety information for PAQ

Computed Descriptors for PAQ

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