Paeoniflorin

Chemical properties

White powder

The Uses of Paeoniflorin

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has broad pharmacological effects, such as analgesic, anti-diuretic，anti-inflammatory，anti-convulsant, vasodilatic, and etc. In a study, paeoniflorin effe

The Uses of Paeoniflorin

antiinflammatory, antispasmodic, antihypertensive, antidiuretic

The Uses of Paeoniflorin

Paeoniflorin is an active compound of the Paeonia root. Paeoniflorin inhibits Aβ25-35-induced mitochondrial dysfunction, which includes decreased mitochondrial membrane potential, increased Bax/Bcl-2 ratio, cytochrome c release and activity of caspase-3 and caspase-9. Paeoniflorin could attenuate or restore the viability loss, apoptotic increase, and ROS production induced by Aβ25-35 in SH-SY5Y cells.

What are the applications of Application

Paeoniflorin is a glycoside that activates Adenosine A1-R

Definition

ChEBI: Paeoniflorin is a terpene glycoside.

General Description

Paeoniflorin has been demonstrated to exert anti-inflammatory and immunomodulatory effects.

Biochem/physiol Actions

Herbal constituent of peony root. It is used in Chinese traditional medicine for its spasmolytic and pain-relieving properties. Exhibits anticoagulant, neuromuscular blocking, cognition-enhancing, immunoregulating, and antihyperglycemic effects.

Safety Profile

Moderately toxic by intravenous route. Mildly toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes.