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HomeProduct name listOxodipine

Oxodipine

Oxodipine Structural

What is Oxodipine?

Enzyme inhibitor

This dihydropyridine-class calcium ion blocker (FW = 359.37 g/mol; CAS 90729-41-2), also known as 4-(1,3-benzodioxol-4-yl)-2,6-dimethyl-1,4- dihydropyridine-3,5-dicarboxylic acid O3 -ethyl,O5 -methyl ester, greatly depresses KCl-induced contraction of rabbit aorta and also decreases the contractile force of rat ventricular strips, the latter with lower potency. Oxodipine markedly shortens cardiac action potentials, and, in rat cultured neonatal ventricular myocytes, oxodipine decreases the L-type Ca2+ current (ICaL) with IC50 of 0.24 μM and is also an effective blocker of T-type Ca2+ current (ICaT) than elgodipine (IC50 = 0.41 μM).

Properties of Oxodipine

Boiling point: 470.0±45.0 °C(Predicted)
Density  1.247±0.06 g/cm3(Predicted)
pka 2.98±0.70(Predicted)

Safety information for Oxodipine

Computed Descriptors for Oxodipine

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