OROTIDINE
- CAS NO.：314-50-1
- Empirical Formula: C10H12N2O8
- Molecular Weight: 288.21
- MDL number: MFCD00057418
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:11
What is OROTIDINE?
The Uses of OROTIDINE
Orotidine is a metabolite of Orotic Acid (O691500); a compound used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.
What are the applications of Application
Orotidine is a nucleoside found naturally in fungi, bacteria and plants, and used as a reference in the research of disease and metabolic deficiencies.
Definition
ChEBI: A nucleoside formed by attaching orotic acid to a ribose ring via a beta1N(1)-glycosidic bond.
Enzyme inhibitor
This water-soluble ribonucleoside (FWfree-acid = 288.21 g/mol; CAS 314-50- 1; lmax of 267 nm in 0.1 N HCl (e = 9570 cm–1M–1; another report lists 9800) and 265 nm in 0.1 N methanolic NaOH (e = 8960 cm–1M–1; another report lists 7800)), first observed in Neurospora crassa, is also foound in the urine of cancer patients treated with 6-azauridine, Orotidine is most likely formed from OMP, its 5’-monophosphate ester and the direct precursor of UMP. Orotidine is readily hydrolyzed in dilute mineral acids. Target(s): orotate phosphoribosyltransferase; orotidine-5’-phosphate decarboxylase.
Properties of OROTIDINE
| Melting point: | >400 °C |
| Density | 1.847±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | 2.62±0.20(Predicted) |
| color | White to Off-White |
Safety information for OROTIDINE
Computed Descriptors for OROTIDINE
New Products
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