OROTIDINE
- CAS NO.：314-50-1
- Empirical Formula: C10H12N2O8
- Molecular Weight: 288.21
- MDL number: MFCD00057418
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-04-24 14:58:11
What is OROTIDINE?
The Uses of OROTIDINE
Orotidine is a metabolite of Orotic Acid (O691500); a compound used in the preparation of therapeutic agents for chronic obstructive pulmonary disease (COPD) treatment.
What are the applications of Application
Orotidine is a nucleoside found naturally in fungi, bacteria and plants, and used as a reference in the research of disease and metabolic deficiencies.
Definition
ChEBI: A nucleoside formed by attaching orotic acid to a ribose ring via a beta1N(1)-glycosidic bond.
Enzyme inhibitor
This water-soluble ribonucleoside (FWfree-acid = 288.21 g/mol; CAS 314-50- 1; lmax of 267 nm in 0.1 N HCl (e = 9570 cm–1M–1; another report lists 9800) and 265 nm in 0.1 N methanolic NaOH (e = 8960 cm–1M–1; another report lists 7800)), first observed in Neurospora crassa, is also foound in the urine of cancer patients treated with 6-azauridine, Orotidine is most likely formed from OMP, its 5’-monophosphate ester and the direct precursor of UMP. Orotidine is readily hydrolyzed in dilute mineral acids. Target(s): orotate phosphoribosyltransferase; orotidine-5’-phosphate decarboxylase.
Properties of OROTIDINE
| Melting point: | >400 °C |
| Density | 1.847±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| form | Solid |
| pka | 2.62±0.20(Predicted) |
| color | White to Off-White |
Safety information for OROTIDINE
Computed Descriptors for OROTIDINE
New Products
AMino-(3-Methylphenyl)-acetic acid 4-Fluorophenylglycine 3-AMINO-3-(2-CHLORO-PHENYL)-PROPIONIC ACID Dimedone 1-N-Boc-3-(aminoethyl)azetidine 1-Boc-3-(cyanomethyl)azetidine 2-Amino-3-Bromopyridine 2-Amino-3-Bromo-5-Nitropyridine Pyridine-N-oxide 4-Hydroxypyridine 2-Hydroxy-6-Picoline 5-Bromo-2-Chloropyridine 2-Amino-4-phenyl-thiazole 4-Chloro-2-methyl quinoline N-(4-Bromophenyl)-2-chloroacetamide 2-Aminobenzo[d]thiazol-4-ol 4-Nitrobenzenesulfonohydrazide 1-(3-Hydroxyphenyl)-2-thiourea Phenyl-boronic acid-d5 10,11-Dihdyro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide-d4 4-(4-(Dimethylamino)-1-(4-fluorophenyl)-1-hydroxybutyl)-3-(hydroxymethyl)benzonitrile 2,6-dimethoxyphenol 2-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)-4-methylpyrimidine N-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)hydrazinecarboxamideRelated products of tetrahydrofuran
You may like
-
1872090-65-7 97-99 %View Details
1872090-65-7 -
3-Benzyl-3,9-diazaspiro [5.5] undecane hydrochloride 1955493-94-3 97-99 %View Details
1955493-94-3 -
1503408-77-2 97-99 %View Details
1503408-77-2 -
1-(3,5-dichlorophenyl)-2,2,2-trifluoroethan-1-ol 97-99 %View Details
1187989-89-4 -
7211-54-3 97-99 %View Details
7211-54-3 -
ethyl 1-(2,4-dichlorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxylate 97-99 %View Details
665020-24-6 -
(S)-2-Bromobutanoic acid 97-99 %View Details
32659-49-7 -
1285573-42-3 Benzo[d]thiazol-3(2H)-yl(3,5-dichloro-4-methoxyphenyl)methanone 97-99 %View Details
1285573-42-3