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Ormosinine

Ormosinine Structural

What is Ormosinine?

Description

A further alkaloid found in various Orrnosia species, the structure of this base has recently been revised, making it the ll-epimer of Panamine (q.v.). It has [α]589 + 9.6° and [α]436 + 14.9°. The dipicrate, m.p. l46-8°C has been prepared but this decomposes when purification by recrystallization is attempted

References

Lloyd, Homing.,J. Arner. Chern. Soc., 80, 1506 (1958)
Naegeli, Wildman, Lloyd., Tetrahedron Lett., 2069 (1963)
Naegeli et al., ibid, 2075 (1963)
Revised structure: Wilson., Chern. Ind., 472 (1965)
Wilson., Tetrahedron, 21,2561 (1965)

Properties of Ormosinine

Melting point: 219-220°
alpha  25436 +16.0°; 25589 +8.9° (c = 1.29 in chloroform)
Density  1.20±0.1 g/cm3(Predicted)
pka 10.91±0.40(Predicted)

Safety information for Ormosinine

Computed Descriptors for Ormosinine

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