OLEANDOMYCIN PHOSPHATE

Description

Oleandomycin is a macrolide antibiotic with a 14-membered lactone constituent. It was found in the culture broth of Streptomyces antibioticus by Pfizer Research Laboratories in 1954. Oleandomycin shows almost the same antimicrobial spectrum and activity as the other macrolide antibiotics. Its serum concentration is low, but its tissue concentration is high enough to provide a therapeutic effect. Oleandomycin phosphate is used orally or intravenously to treat pyoderma, sepsis, meningitis, surgical and abdominal infections, respiratory tract and urinary tract infections, and other infections caused by Staphylococci, Streptococci, Corynebacterium, Neisseria, and Mycoplasma. Oleandomycin is also used as a feed additive and therapeutic agent for animals.

The Uses of OLEANDOMYCIN PHOSPHATE

Oleandomycin Phosphate is an antibiotic substance produced by Streptomyces antibioticus no. ATCC 11891. Antibacterial.

brand name

Matromycin (Pfizer).

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of POx and NOx. See also PHOSPHATES.