Octamethyltrisiloxane
- CAS NO.:107-51-7
- Empirical Formula: C8H24O2Si3
- Molecular Weight: 236.53
- MDL number: MFCD00008264
- EINECS: 203-497-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-12 09:12:00
What is Octamethyltrisiloxane?
Chemical properties
Octamethyltrisiloxane is clear colourless liquid.
The Uses of Octamethyltrisiloxane
Octamethyltrisiloxane is a linear silicone oligomer. It is used as an excipient Dimethicones in pharmaceutical and cosmetic applications can provide long lasting lubricant, smooth feel and spreads easily. Studies demonstrate that it is able to maintain the conformational stability of certain adsorbed proteins such as bovine serum albumin (BSA). Used in the methylation of mercury(II) salts.
What are the applications of Application
As a basis for silicone oils or fluids designed to withstand extremes of temp; as a foam suppressant in petroleum lubricating oil.
Definition
ChEBI: Octamethyltrisiloxane is an organosiloxane that is trisiloxane in which all the hydrogens have been replaced by methyl groups.
General Description
Poly(dimethylsiloxane) (PDMS), also known as dimethicone, is an organosilicon compound that is widely used as a siloxane based elastomer. It is a hydrophobic material with attractive physical and chemical properties such as elasticity, optical transparency, tunable surface chemistry, and low electrical conductivity.
Flammability and Explosibility
Flammable
Purification Methods
Distil it twice, the middle fraction from the first distillation is again distilled, and the middle fraction of the second distillation is used. [Patnode & Wilcock J Am Chem Soc 68 358, Wolcock J Am Chem Soc 68 691 1946, Thompson J Chem Soc 1908 1953, Beilstein 4 IV 4115.]
Properties of Octamethyltrisiloxane
| Melting point: | -82 °C (lit.) |
| Boiling point: | 153 °C (lit.) |
| Density | 0.82 g/mL at 25 °C (lit.) |
| vapor density | >1 (vs air) |
| vapor pressure | 5.3hPa at 25℃ |
| refractive index | n |
| Flash point: | 99 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), DMSO, Methanol (Slightly) |
| form | liquid |
| color | Colourless to Pale Yellow |
| Specific Gravity | 0.82 |
| Water Solubility | 34μg/L at 23℃ |
| Hydrolytic Sensitivity | 1: no significant reaction with aqueous systems |
| Merck | 14,6748 |
| BRN | 1753063 |
| Dielectric constant | 2.3(20℃) |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 107-51-7(CAS DataBase Reference) |
| EPA Substance Registry System | Trisiloxane, octamethyl- (107-51-7) |
Safety information for Octamethyltrisiloxane
| Signal word | Warning |
| Pictogram(s) |
![]() Flame Flammables GHS02 |
| GHS Hazard Statements |
H226:Flammable liquids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge. |
Computed Descriptors for Octamethyltrisiloxane
New Products
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