O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
Synonym(s):O-(1,1-Dimethylethyl)hydroxylamine hydrochloride;tert-Butoxyamine hydrochloride;2-Aminooxy-2-methylpropane hydrochloride
- CAS NO.:39684-28-1
- Empirical Formula: C4H12ClNO
- Molecular Weight: 125.6
- MDL number: MFCD00043272
- EINECS: 254-590-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:24:16
What is O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE?
Chemical properties
White crystalline powder
The Uses of O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
O-tert-Butylhydroxylamine Hydrochloride is an reactant used in various synthesis of biologically active molecules such as camptothecin derivatives that exerts anti-tumor activity, oxime derivatives as GPR119 agonists and their preparation and highly Potent Matrix Metalloproteinase Inhibitors.
The Uses of O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
Reactant involved in synthesis of biologically active molecules including:• ;CGS 25966 derivatives for use as MMP inhibitors1• ;Imidazolidinedione derivatives for use as antimalarial treatments2• ;Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists3• ;Rab proteins for isoprenylation and geranylgeranylation inhibition4Reactant involved in:• ;Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents5• ;Double allylic alkylation of indole-2-hydroxamates6• ;SN2 substitution reactions at amide nitrogens7• ;Photoc
The Uses of O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
Reactant involved in synthesis of biologically active molecules including:
- CGS 25966 derivatives for use as MMP inhibitors
- Imidazolidinedione derivatives for use as antimalarial treatments
- Pyrimidine ribonucleotide analogs as P2Y6 receptor agonists
- Rab proteins for isoprenylation and geranylgeranylation inhibition
Reactant involved in:
- Synthesis of N-(arylethyl)-O-tert-butylhydroxamates for use as Weinreb amide equivalents
- Double allylic alkylation of indole-2-hydroxamates
- SN2 substitution reactions at amide nitrogens
- Photocycloaddition to C=N bonds for synthesis of 1,3-diazepines
What are the applications of Application
O-tert-Butylhydroxylamine hydrochloride is for preparing N-tert-butoxyamino acids
Properties of O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
| Melting point: | 158-159 °C(lit.) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: soluble0.5g/10 mL |
| form | powder to crystal |
| color | White to Almost white |
| BRN | 3668106 |
Safety information for O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
| Signal word | Warning |
| Pictogram(s) |
![]() Flame Flammables GHS02 |
| GHS Hazard Statements |
H228:Flammable solids |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. |
Computed Descriptors for O-TERT-BUTYLHYDROXYLAMINE HYDROCHLORIDE
New Products
2-(3-Methyl-1,2,4-oxadiazol-5-yl)acetic acid (as potassium salt) 2-fluoro-4-iodoaniline 4-Iodo-3,5-dimethylbenzonitrile Atorvastatin amide impurity/Atorvastatin EP Impurity F(Calcium Salt) Lantanoprost rc B Clidinium Bromide Impurity Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity N-Nitroso hydroxy Cetrizine EP Impurity-A (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine 6-bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-Fluoro-4-nitrotoluene 1-(2-amino-5-hydroxy phenyl)propan-1-one (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 3-(Dimethylamino)benzoic acid 2-Amino-5-chloropyridine 4-(Methylamino)-3-nitrobenzoic Acid 5-Chloro-2-Nitroaniline 3,5-dibenzyloxy Acetophenone 2,4-Diamino-6-hydroxypyrimidine 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3,4 Diethoxy BenzylcyanideRelated products of tetrahydrofuran

![1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium chloride monohydrochloride](https://img.chemicalbook.in/CAS/GIF/73547-70-3.gif)






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