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HomeProduct name listO-Methyl-D-prolinol

O-Methyl-D-prolinol

Synonym(s):O-Methyl-D-prolinol

O-Methyl-D-prolinol Structural

What is O-Methyl-D-prolinol?

Chemical properties

Colorless liquid

The Uses of O-Methyl-D-prolinol

(2R)-2-(Methoxymethyl)-pyrrolidine is a useful synthetic intermediate. It can be used to prepare pyrazolo[3,4-d]pyrimidinylamino pyrrolecarboxamides for potential use as antitumor agents with reduced neutropenic side effects. It can be also used to synthesize heteroaryl pyrimidinylacetamides as A2A receptor antagonists.

Properties of O-Methyl-D-prolinol

Boiling point: 61-62°C 40mm
alpha  -2.4o (C=2% IN BENZENE)
Density  0.932 g/mL at 20 °C(lit.)
refractive index  n20/D 1.446
Flash point: 45°C
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
pka 10.01±0.10(Predicted)
form  Liquid
color  Clear colorless
optical activity [α]20/D 2.4±0.3°, c = 2% in benzene
Sensitive  Air Sensitive
BRN  4229755
CAS DataBase Reference 84025-81-0(CAS DataBase Reference)

Safety information for O-Methyl-D-prolinol

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for O-Methyl-D-prolinol

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