O-DESMETHYLGALANTHAMINE
- CAS NO.：60755-80-8
- Empirical Formula: C16H19NO3
- Molecular Weight: 273.33
- MDL number: MFCD07369289
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-03-13 15:00:32
What is O-DESMETHYLGALANTHAMINE?
Chemical properties
Pale Yellow Powder
The Uses of O-DESMETHYLGALANTHAMINE
A metabolite of Galanthamine, a selective acetylcholinesterase inhibitor
The Uses of O-DESMETHYLGALANTHAMINE
A metabolite of Galanthamine (G188500), a selective acetylcholinesterase inhibitor.
The Uses of O-DESMETHYLGALANTHAMINE
Sanguinine has a more potent acetylcholinesterase inhibitory activity than galanthamine due to an extra hydroxyl group available for potential interaction with acetylcholinesterase. Sanguinine, in turn, is 10-fold more selective than galanthamine for acetylcholinesterase (AChE) vs. butyrylcholinesterase (BuChE). The lack of AChE inhibitory activity of lycoramine and epinorlicoramine could be due to the occurrence of a double bond in ring C, which does not allow these alkaloids to have the same spatial configuration as the active alkaloids of this series.
What are the applications of Application
O-Desmethyl galanthamine is a major galanthamine metabolite
Definition
ChEBI: Sanguinine is a benzazepine.
Properties of O-DESMETHYLGALANTHAMINE
| Melting point: | 227-230°C (dec.) |
| Boiling point: | 451.9±45.0 °C(Predicted) |
| Density | 1.37±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO: soluble |
| form | A solid |
| pka | 9.39±0.40(Predicted) |
| color | White to off-white |
| CAS DataBase Reference | 60755-80-8 |
Safety information for O-DESMETHYLGALANTHAMINE
Computed Descriptors for O-DESMETHYLGALANTHAMINE
New Products
Methyl N-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-N-nitroso-L-valinate Levofloxacin - Impurity B/ Levofloxacin Related Compound A Ivabradine R isomer Escitalopram - Impurity K Escitalopram Cyno dilol Impurity Paroxetine EP impurity I/Paroxetine Anhydrous EP Impurity I 2-Amino-5-Bromo-6-Chloropyridine 3-Amino-5-bromopicolinic acid 1-(7,8-Dinitro-4,5-dihydro-1H-1,5-methanobenzo[d]azepin-3(2H)-yl)-2,2,2-trifluoroethanone 2-Amino-3-Bromo-5-Cyanopyridine 2-Amino-3-Chloropyridine 2,5-Dibromo-3-MethylpyridineRelated products of tetrahydrofuran
You may like
-
60755-80-8 O-Desmethyl galantamine 98%View Details
60755-80-8 -
17471-10-2 Diphenhydramine EP impurity-A /Diphenhydramine Related Compound A NLT 95%View Details
17471-10-2 -
Dorzolamide Related Compound B/Dorzolamide EP Impurity B NLT 95%View Details
120279-90-5 -
76824-16-3 Famotidine - Impurity D NLT 95%View Details
76824-16-3 -
118-23-0 NLT 95%View Details
118-23-0 -
Miconazole EP Impurity F/ Miconazole USP Related Compound F 47447-55-2 NLT 95%View Details
47447-55-2 -
2407630-84-4 NLT 95%View Details
2407630-84-4 -
573704-41-3 NLT 95%View Details
573704-41-3