NSC 625987
Synonym(s):1,4-Dimethoxyacridine-9(10H)-thione;Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem
- CAS NO.：141992-47-4
- Empirical Formula: C15H13NO2S
- Molecular Weight: 271.33
- MDL number: MFCD08276925
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-12-10 09:00:29
What is NSC 625987?
The Uses of NSC 625987
NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor.
What are the applications of Application
NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor
Definition
ChEBI: 1,4-dimethoxy-10H-acridine-9-thione is a member of acridines.
Biological Activity
Cyclin-dependent kinase (cdk) 4 inhibitor (IC 50 = 0.2 μ M at cdk4/cyclin D1). Displays > 500-fold selectivity over cdk2 (IC 50 > 100 μ M for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).
Properties of NSC 625987
| storage temp. | 2-8°C |
| solubility | DMSO: 14 mg/mL |
| form | Powder |
| color | Brown to khaki |
Safety information for NSC 625987
Computed Descriptors for NSC 625987
New Products
Indole Methyl Resin tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Boc-His(Boc)-OH 2-CTC Resin 4-Chloro-7-tosy1-7Hpyrrolo[2,3-d]pyrimidine 5,7-Dibromo-1H-indole 2,5-dichloro-N-hydroxy-4,6-dimethylpyridine-3-carboximidamide 2,2-Dimethoxy-7-azaspiro[3.5]nonane hydrochloride 4-chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDIIMIDAZOLE 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID 4-((2-hydroxyethyl)thio)benzoic acid 1-(TERT-BUTOXYCARBONYL)-2-PYRROLIDINONE Methyl 6-methylnicotinate 3-Pyridineacrylic acid tert-Butyl carbazate TETRAHYDRO-2H-PYRAN-3-OL 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile 2,4-dihydroxybenzaldehyde 1,3-Diethyl-1,3-Diphenylurea Methyl 2-methylquinoline-6-carboxylateRelated products of tetrahydrofuran
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