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HomeProduct name listNSC 625987

NSC 625987

Synonym(s):1,4-Dimethoxyacridine-9(10H)-thione;Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem

NSC 625987 Structural

What is NSC 625987?

The Uses of NSC 625987

NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor.

What are the applications of Application

NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor

Definition

ChEBI: 1,4-dimethoxy-10H-acridine-9-thione is a member of acridines.

Biological Activity

Cyclin-dependent kinase (cdk) 4 inhibitor (IC 50 = 0.2 μ M at cdk4/cyclin D1). Displays > 500-fold selectivity over cdk2 (IC 50 > 100 μ M for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).

Properties of NSC 625987

storage temp.  2-8°C
solubility  DMSO: 14 mg/mL
form  Powder
color  Brown to khaki

Safety information for NSC 625987

Computed Descriptors for NSC 625987

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