NSC 625987
Synonym(s):1,4-Dimethoxyacridine-9(10H)-thione;Cdk4 Inhibitor II, NSC 625987 - CAS 141992-47-4 - Calbiochem
- CAS NO.：141992-47-4
- Empirical Formula: C15H13NO2S
- Molecular Weight: 271.33
- MDL number: MFCD08276925
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-07-16 07:06:08
What is NSC 625987?
The Uses of NSC 625987
NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor.
What are the applications of Application
NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor
Definition
ChEBI: 1,4-dimethoxy-10H-acridine-9-thione is a member of acridines.
Biological Activity
Cyclin-dependent kinase (cdk) 4 inhibitor (IC 50 = 0.2 μ M at cdk4/cyclin D1). Displays > 500-fold selectivity over cdk2 (IC 50 > 100 μ M for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).
Properties of NSC 625987
| storage temp. | 2-8°C |
| solubility | DMSO: 14 mg/mL |
| form | Powder |
| color | Brown to khaki |
Safety information for NSC 625987
Computed Descriptors for NSC 625987
New Products
Dibenzoyl-L-tartaric acid Anhydrous (Resolution Reagent) 2-Bromo-5-hydroxybenzoic acid. 1-(4-methoxyphenyl)-4-(4-Nitrophenyl)Piperazine (IT-1) Dibenzo[b,f][1,4]thiazepin-11(10H)-one 1-Benzhydrylazetane-3-carbonitrile AMINO-(3-CHLORO-PHENYL)-ACETIC ACID 2-(2-Chlorophenyl)glycine 8-oxa-1,3-diazaspiro[4.5]decane-2,4-dione (±)-amino(2-fluorophenyl)acetic acid 2'-Fluoroacetophenone PHOSPORIC ACID-D3 85 W% IN D2O METHANE-D3-SULFONYL CHLORIDE 3-BROMO PYRIDINE-D4 2-BROMOACETYL BROMIDE-D2 DEUTERIUM OXIDE FOR NMR BENZENE-D6 1-Acetyl-4-(4-hydroxyphenyl)piperazine 1-(3-Chlorophenyl)piperazine hydrochlorideRelated products of tetrahydrofuran
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