N,N-Dimethyl-2-chloroacetoacetamide
Synonym(s):2-Chloro-N,N-dimethylacetoacetamide;DMCAA
- CAS NO.：5810-11-7
- Empirical Formula: C6H10ClNO2
- Molecular Weight: 163.6
- MDL number: MFCD00042937
- EINECS: 227-372-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-09-12 18:54:55
What is N,N-Dimethyl-2-chloroacetoacetamide?
Chemical properties
Clear, light yellow liquid
The Uses of N,N-Dimethyl-2-chloroacetoacetamide
N,N-Dimethyl-2-chloroacetoacetamide is a useful reagent in the synthesis of antiinflammatory 2-(3-pyridyl)thiazoles and other useful organic compounds.
The Uses of N,N-Dimethyl-2-chloroacetoacetamide
Intermediate for synthesis. Contact
General Description
N,N-Dimethyl-2-chloroacetoacetamide is an active component of Aframomum danielli spice powder.
Hazard
A poison by skin contact. Moderately toxic by ingestion. A severe skin and eye irritant.
Properties of N,N-Dimethyl-2-chloroacetoacetamide
| Melting point: | 36 °C(lit.) |
| Boiling point: | 95 °C0.7 mm Hg(lit.) |
| Density | 1.203 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | >230 °F |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Oil |
| pka | 10.05±0.46(Predicted) |
| color | Yellow to Dark Yellow |
| BRN | 1761325 |
| EPA Substance Registry System | Butanamide, 2-chloro-N,N-dimethyl-3-oxo- (5810-11-7) |
Safety information for N,N-Dimethyl-2-chloroacetoacetamide
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H351:Carcinogenicity H412:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N,N-Dimethyl-2-chloroacetoacetamide
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