N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE
Synonym(s):N,N-Bis[2-(tosyloxy)ethyl]-p-toluenesulfonamide;N,O,O′-Tritosyldiethanolamine
- CAS NO.：16695-22-0
- Empirical Formula: C25H29NO8S3
- Molecular Weight: 567.69
- MDL number: MFCD00026000
- EINECS: 412-920-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-13 11:17:02
![N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE Structural](https://img.chemicalbook.in/CAS/GIF/16695-22-0.gif)
What is N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE?
The Uses of N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE
N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE used to prepare selectively protected aza-macrocycles,1 carbon-bridged metallacarboranes,2 and tetrakis(phosphonomethyl)-substituted cyclododecanes.3
The Uses of N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE
N,N-Bis[2-(p-tolylsulfonyloxy)ethyl]-p-toluenesulfonamide may be used in the preparation of :
- 2-(p-benzamidobenzyl)-1,4,7-tris(p-tolylsulfonyl)-1,4,7-triazacyclononane, via reaction with N,N′-bis(p-tolylsulfonyl)-1-(p-benzamidobenzyl)ethylenediamine
- selectively protected aza-macrocycles
- carbon-bridged metallacarboranes
- tetrakis(phosphonomethyl)-substituted cyclododecanes
What are the applications of Application
N,N-Bis[2-(p-tolylsulfonyloxy)ethyl]-p-toluenesulfonamide is a chemical used in the preparation of azamacrocycles
Properties of N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE
| Melting point: | 92-98 °C(lit.) |
| Boiling point: | 732.4±70.0 °C(Predicted) |
| Density | 1.345±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| pka | -9.29±0.70(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| BRN | 2406580 |
Safety information for N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P272:Contaminated work clothing should not be allowed out of the workplace. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention. |
Computed Descriptors for N,N-BIS[2-(P-TOLYLSULFONYLOXY)ETHYL]-P-TOLUENESULFONAMIDE
New Products
Cyclopentane-1,2-dione Isopropyl amine Hydrochloride 2-Bromo-5-iodopyridine 3-Aminophenylacetic acid Amino-4-methoxyben-zeneacetic acid 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile 1-AMino-cyclobutaneMethanol HCl (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 2-(3-aminopropylamino)ethanol 4-(5-(bis-(2-hydroxy ethyl)amino)-1-methyl-1h-benzoimidazol-2-yl)-butyric acid isopropyl ester. 4-cyano 3-(trifluoromethyl)-n-(2,3-epoxy-2-methylpropionyl)aniline 2-(3-amino propyl amino) ethyl bromide di hydrobromide N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropionamide N-[(1S)-1-benzyl-2-({(1R)-3-methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0~2,6~]dec-4-yl]butyl}amino)-2-oxoethyl]-2-pyrazinecarboxamide 2-Chloro Benzylcyanide 3-chlorobenzyl cyanide 3-Hydroxypropionitrile 4-Bromo BenzylcyanideRelated products of tetrahydrofuran
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