N,N'-BIS(2-HYDROXYETHYL)-UREA
- CAS NO.：15438-70-7
- Empirical Formula: C5H12N2O3
- Molecular Weight: 148.16
- MDL number: MFCD00522193
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-05-28 01:03:37
What is N,N'-BIS(2-HYDROXYETHYL)-UREA?
Preparation
Excess ethanolamine and DMDTC were mixed and heated at 60℃ for 15 h. The released malodorous methyl sulfide by-product was absorbed and oxidized by NaOCl solution. When the reaction was complete, the unreacted ethanolamine was removed under reduced pressure by simple distillation, leaving a crude mixture of oxazolidinone and bis(2-hydroxyethyl)urea, which was further purified by recrystallization from methanol/ethyl acetate (1:4.5) to give N,N'-bis(2-hydroxyethyl)urea as colorless crystals.
Properties of N,N'-BIS(2-HYDROXYETHYL)-UREA
| Melting point: | 83 °C |
| Boiling point: | 445.1±30.0 °C(Predicted) |
| Density | 1.226±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under inert atmosphere |
| solubility | DMSO (Slightly) |
| form | Solid |
| pka | 13.09±0.46(Predicted) |
| color | Off-White to Light Beige |
| EPA Substance Registry System | Urea, N,N'-bis(2-hydroxyethyl)- (15438-70-7) |
Safety information for N,N'-BIS(2-HYDROXYETHYL)-UREA
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for N,N'-BIS(2-HYDROXYETHYL)-UREA
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