NIFEDIPINE-D6
- CAS NO.：1188266-14-9
- Empirical Formula: C17H12D6N2O6
- Molecular Weight: 352.37
- MDL number: MFCD08063477
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-01-05 11:31:08
What is NIFEDIPINE-D6?
Description
Nifedipine-d6 is intended for use as an internal standard for the quantification of nifedipine by GC- or LC-MS. Nifedipine is a dihydropyridine L-type calcium channel blocker that reduces the amplitude of spontaneous contractions in isolated rabbit ileum when used at a concentration of 1 μM. Nifedipine (1 μM) reduces TGF-β-induced calcium oscillations in human fibroblasts and prevents impairment of lung function in a mouse model of pulmonary fibrosis induced by bleomycin when administered at a dose of 10 mg/kg per day. It also reduces increases in mean arterial blood pressure induced by angiotensin II in spontaneously hypertensive rats when administered at a dose of 10 μg/kg. Formulations containing nifedipine have been used in the treatment of hypertension and angina.
Chemical properties
Yellow Solid
The Uses of NIFEDIPINE-D6
(Nifedipine-d6) Labeled Nifedipine, intended for use as an internal standard for the quantification of Nifedipine by GC- or LC-mass spectrometry.
The Uses of NIFEDIPINE-D6
Used as an antihypertensive and antianginal. A labelled dihydorpyridine calcium channel blocker.
What are the applications of Application
Nifedipine-d6 is an isotopically labeled Ca channel blocker
Properties of NIFEDIPINE-D6
| Melting point: | 164-165°C |
| storage temp. | -20°C Freezer |
| solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| color | Yellow |
Safety information for NIFEDIPINE-D6
Computed Descriptors for NIFEDIPINE-D6
NIFEDIPINE-D6 manufacturer
SYNTHENTA PVT LTD
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