NF110
- CAS NO.：111150-22-2
- Empirical Formula: C41H28N6O17S4.4Na
- Molecular Weight: 1096.92
- MDL number: MFCD09038569
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-04-17 18:22:24
What is NF110?
The Uses of NF110
NF 110 is a potent P2X3 receptor antagonist.
What are the applications of Application
NF 110 is a potent P2X3 receptor antagonist
Biological Activity
High affinity P2X 3 receptor antagonist (K i values are 36, 82 and 4144 nM for P2X 3 , P2X 1 and P2X 2 recombinant receptors respectively). Shows no activity at P2Y 1 , P2Y 2 and P2Y 11 receptors (IC 50 > 10 μ M). Potently inhibits α , β -meATP-evoked desensitizing currents in rat DRG neurons (IC 50 = 527 nM). Shows antitumor activity against several tumor types.
Storage
Desiccate at RT
Properties of NF110
| storage temp. | Desiccate at RT |
| form | Powder |
| color | White to off-white |
| Water Solubility | Soluble to 40 mM in water |
Safety information for NF110
Computed Descriptors for NF110
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