NEUROMEDIN B

Description

NMB is distributed in the central nervous system as well as the gastrointestinal tract, and has many regulatory functions in physiology such as exocrine and endocrine secretions, smooth muscle contraction, feeding, energy homeostasis, body temperature, nociception, itch perception, anxiety, sighing, and cell growth.

The Uses of NEUROMEDIN B

Neuromedin B, porcine is an endogenous activator for the NMBR (neuromedin B receptor).

What are the applications of Application

Neuromedin B is an endogenous activator for NMBR (neuromedin B receptor)

General Description

Neuromedin B (NMB) belongs to the bombesin (BN)-like peptide family in mammals. It is located in the gastrointestinal tract and central nervous system.

Biochem/physiol Actions

Neuromedin B (NMB) exhibits its effects by binding to the cell surface receptors. It facilitates its action on several contractile organs including, the stomach, intestine, esophagus, gall bladder, urinary bladder, and uterus. It also plays a role in food intake, hypothermia, and thermoregulation. NMB is involved in exocrine and endocrine secretion of gastrin, insulin, cholecystokinin, enteroglucagon, and gastric inhibitory peptide. It also acts as an autocrine growth factor in non-small cell lung cancer.

Storage

Store at -20°C