Nefiracetam
Synonym(s):(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide);DM-9384
- CAS NO.：77191-36-7
- Empirical Formula: C14H18N2O2
- Molecular Weight: 246.3
- MDL number: MFCD00209882
- EINECS: 636-080-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2026-11-04 17:01:59
What is Nefiracetam?
The Uses of Nefiracetam
Nefiracetam improves post-ischemia evoke-nonconvulsive seizure by altering pro-inflammatory cytokines.
The Uses of Nefiracetam
analgesic, antiinflammatory
What are the applications of Application
Nefiracetam is activator of L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems
Definition
ChEBI: Nefiracetam is an organooxygen compound and an organonitrogen compound. It is functionally related to an alpha-amino acid.
Biological Activity
Cognitive enhancer that displays various pharmacological effects. Activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. Displays potent neuroprotective action in the retinal ischemia-reperfusion model in vivo .
Storage
Store at RT
Properties of Nefiracetam
| Melting point: | 151-155°C |
| Boiling point: | 458.5±33.0 °C(Predicted) |
| Density | 1.187±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO: >5mg/mL |
| form | solid |
| pka | 13.77±0.70(Predicted) |
| color | white to off-white |
| Merck | 14,6439 |
| InChI | InChI=1S/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17) |
| CAS DataBase Reference | 77191-36-7(CAS DataBase Reference) |
Safety information for Nefiracetam
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for Nefiracetam
| InChIKey | NGHTXZCKLWZPGK-UHFFFAOYSA-N |
| SMILES | N1(CC(NC2=C(C)C=CC=C2C)=O)CCCC1=O |
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