DMT-2′O-MOE-rMeC(bz) Phosphoramidite
- CAS NO.：163759-94-2
- Empirical Formula: C50H60N5O10P
- Molecular Weight: 922.01
- MDL number: MFCD00792624
- Update Date: 2025-08-21 22:16:43
What is DMT-2′O-MOE-rMeC(bz) Phosphoramidite?
The Uses of DMT-2′O-MOE-rMeC(bz) Phosphoramidite
N4-Benzoyl-5''-O-DMT-2''-O-methylcytidine 3''-CE phosphoramidite (CAS# 163759-94-2) is a nucleotide used in the stereoselective synthesis of nucleoside alkyl-phosphonates.
General Description
DMT-2′O-MOE-rMeC(bz) Phosphoramidite (N4-Bz-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine-3'-CED-phosphoramidite) is a phosphoramidite that belongs to the family of amides of trivalent phosphorus acid H3PO3. N4-Bz-5'-O-DMTr-2'-O-(2-methoxyethyl)-5-methylcytidine-3'-CED-phosphoramidite features a 2'-O-MOE group and can be incorporated into oligonucleotide phosphoramidites for antisense RNA. The 2'-MOE backbone enhances duplex stability, nuclease resistance, and has low toxicity.
Properties of DMT-2′O-MOE-rMeC(bz) Phosphoramidite
| storage temp. | Store at -20°C |
| pka | 8.59±0.40(Predicted) |
| form | Powder |
| color | White to Off-white |
Safety information for DMT-2′O-MOE-rMeC(bz) Phosphoramidite
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P312:Call a POISON CENTER or doctor/physician if you feel unwell. P362:Take off contaminated clothing and wash before reuse. P302+P352:IF ON SKIN: wash with plenty of soap and water. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for DMT-2′O-MOE-rMeC(bz) Phosphoramidite
| InChIKey | FLIGVMLIIDVDSN-SQULMOJWNA-N |
| SMILES | O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=C(C)C(NC(=O)C3=CC=CC=C3)=NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,45,51,r| |
DMT-2′O-MOE-rMeC(bz) Phosphoramidite manufacturer
DR ACHARYA LABORATORIES PVT LTD
1Y
Phone:+91-9820308443
Whatsapp: +91-9820308443
product: N4-benzoyl-5’-O-DMT-2’-O-(2-methoxyethyl)-5-methylcytidine-3'-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite, MOEC, Phosphoramidite, 98%
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