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HomeProduct name listN-Nitroso-N-Methyl-4-Aminobutyric Acid

N-Nitroso-N-Methyl-4-Aminobutyric Acid

N-Nitroso-N-Methyl-4-Aminobutyric Acid Structural

What is N-Nitroso-N-Methyl-4-Aminobutyric Acid?

Chemical properties

Yellow Oil

The Uses of N-Nitroso-N-Methyl-4-Aminobutyric Acid

This N-nitrosamino acid has been isolated and identified in various types of tobacco, inlcluding snuff, chewing and pipe tobacco, cigars and cigarettes. The occurence of N-nitrosamino acids are highly correlated with levels of tobacco-specific N-nitrosamines which are known carcinogens in a wide range of animal species.

What are the applications of Application

N-Nitroso-N-methyl-4-aminobutyric Acid is a compound found in various tobacco types

Definition

ChEBI: N-nitroso-N-methyl-4-aminobutyric acid is a nitrosamine that has methyl and 3-carboxypropyl substituents. It is a tobacco-derived nitrosamino acid that is a known animal and potential human carcinogen. It induces bladder transitional cell carcinomas in rats and has recently been identified as a contaminant in certain blood pressure medications. It has a role as a carcinogenic agent, a rat metabolite, a xenobiotic metabolite and a plant metabolite. It is a monocarboxylic acid and a nitrosamine.

Properties of N-Nitroso-N-Methyl-4-Aminobutyric Acid

Melting point: >25 °C
Boiling point: 265.74°C (rough estimate)
Density  1.3394 (rough estimate)
refractive index  1.4954 (estimate)
storage temp.  Hygroscopic, -20°C Freezer, Under Inert Atmosphere
solubility  Chloroform (Soluble), Dichloromethane (Slightly), Ethyl Acetate (Slightly), Meth
form  Solid
pka 4.57±0.10(Predicted)
color  Off-White to Yellow Oil to
Stability: Hygroscopic

Safety information for N-Nitroso-N-Methyl-4-Aminobutyric Acid

Computed Descriptors for N-Nitroso-N-Methyl-4-Aminobutyric Acid

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