N-nitroso-3-hydroxypiperidine
- CAS NO.：55556-85-9
- Empirical Formula: C5H10N2O2
- Molecular Weight: 130.15
- MDL number: MFCD01699404
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:51
What is N-nitroso-3-hydroxypiperidine?
The Uses of N-nitroso-3-hydroxypiperidine
(S)-1-Nitrosopiperidin-3-ol is an intermediate in synthesizing Ibrutinib-d4 (I124971), a labelled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.
Safety Profile
Questionable carcinogen withexperimental tumorigenic data. Human mutation datareported. Many N-nitroso compounds are carcinogens.When heated to decomposition it emits toxic fumes ofNOx.
Properties of N-nitroso-3-hydroxypiperidine
| Boiling point: | 240.83°C (rough estimate) |
| Density | 1.2268 (rough estimate) |
| refractive index | 1.4954 (estimate) |
| solubility | soluble in Dichloromethane; Methanol |
| form | Oil |
| color | Yellow |
Safety information for N-nitroso-3-hydroxypiperidine
Computed Descriptors for N-nitroso-3-hydroxypiperidine
New Products
Cyclopentane-1,2-dione 2,6-Dibromoaniline (RS)-beta-Amino-beta-(4-bromophenyl)propionic acid 1-AMino-cyclobutaneMethanol HCl TETRABUTYLAMMONIUM CYANIDE 3-Amino-3-(3-fluorophenyl)propanoic acid 3-Amino-3-(4-methylphenyl)propionic acid 3-AMINO-3-(3-CHLORO-PHENYL)-PROPIONIC ACID Cefuroxime EP Impurity-A N-Nitroso hydroxy Cetrizine EP Impurity-A Noradrenaline EP Impurity D/Noradrenaline Methyl Ether Cetirizine EP Impurity A/Cetirizine CBHP Impurity Lantanoprost rc B Clidinium Bromide Impurity 4 - fluoro- 2 - methoxy- 5 - nitroaniline 1-(2-amino-5-hydroxy phenyl)propan-1-one tert-butyl 4-(6-((7-cyclo pentyl -6-(dimethyl carbamoyl) -7H-pyrrolo [2,3-d]pyrimidin-2-yl) amino)pyridin-3-yl) piperazine-1-carboxylate 2-amino-5-nitrobenzonitrile (4-Fluoro-2-methoxy-5-nitro- phenyl)-[4- (1-methyl-1H- indol-3- yl)-pyrimidin-2-yl]- amine (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3- amine 2-Chloro Benzylcyanide 3,4 Diethoxy Benzylcyanide 3,4 Dimethoxy Benzylcyanide 3-chlorobenzyl cyanideRelated products of tetrahydrofuran
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