N-METHYLPARAVALLARIDINE

Empirical Formula: C23H35O3N
Molecular Weight: 0

What is N-METHYLPARAVALLARIDINE?

Description

A minor constituent of Paravallaris microphylla, this alkaloid is laevorotatory with [α]²⁰_D - 49° (c 0.29, CHCI3). Treatment with AC20 in pyridine yields the O-acetate, m.p. 170°C; [α]²⁰_D - 43° (c 0.23, CHCI3). Catalytic hydrogenation over Pt02 gives the dihydro derivative, m.p. 237°C; [α]²⁰_D - 21° (c 0.28, CHCI3) which furnishes the corresponding O-acetate, m.p. 176°C; [α]²⁰_D - 25° (c 0.16, CHCI3). By comparison with Paravallaridine (q.v.), the structure of the alkaloid is shown to be N-methyl-16-a-paravallarine.

References

LeMen, Kan, Beugelmans., Bull. Soc. Chim. Fr., 597, 1306 (1963)
See also:
Bellon., French Patent, Fr. M 1915, 12 August, 1963

Properties of N-METHYLPARAVALLARIDINE

Melting point:

200°C

Safety information for N-METHYLPARAVALLARIDINE

Computed Descriptors for N-METHYLPARAVALLARIDINE

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